Testosterone melting fat and saving lives: Major study over a dozen years

 Quite a few hundred fat older German men participated in the study over a dozen years and all the testosterone injections were done by the doctors.  No one dropped out of the study by Dr. Saad's team.  The control group gained an average of ten pounds and about a third died of all causes with any major cardiovascular events.  The injected group lost an average of over fifty pounds and less than a tenth died, mostly accientally.

After 11 years of data collection in the registry (covering the period 2004-19 with all patients having at least 11 years of data) weight (kg) decreased by a mean of 23kg in the T group (from 114kg to 89kg before adjustment, and to 87 kg after adjustment for baseline age, waist circumference, weight, fasting glucose, systolic and diastolic blood pressure, total cholesterol, HDL, LDL, triglycerides and the quality of life scale AMS). Conversely, mean weight increased by 6kg in the control group. In percentage terms, the results were similar – with the T-group losing an average of 20% bodyweight, whereas controls increased by 6%.

There was also a significant mortality difference between groups: 21 patients (7.6%) died in the T-group and 63 (32.3%) in the control group. More than a quarter of men (28%) in the control group had a heart attack, and 53 (27.2%) a stroke. There were no major cardiovascular events in the T-group. All the deaths in the T-group were related to traffic and sport accidents and post-surgical infections.