Thursday, 30 September 2021

Peptide drops that replicate and sometimes concentrate nucleic acids: Missing link in evolution of life on earth

“The origin of molecular assemblies that proliferate from small molecules has remained a mystery for about a hundred years since the advent of the chemical evolution scenario. It has been the missing link between chemistry and biology in the origin of life.   ...  Researchers .set out to recreate this kind of self-propagating protocell in the lab. They started by combining amino acid derivatives to create a new small molecule that was primed to self-assemble into primitive cells. They added this mix to water at room temperature and normal atmospheric pressure,...   The molecules condensed into peptides, which then formed droplets suspended in the water. When more amino acids were added – as might occur in nature – the droplets not only grew in size, but began to divide. ....  Most intriguingly, some of the droplets concentrated nucleic acids – macromolecules that can carry genetic information. Those droplets that did so were more likely to survive in the environment".

What's not to like:  A replicative process that preserves and even concentrates high value information.

Information from Muneyuki Matsuo posted at Newatlas.com

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